My Friend's Little Sister Has It In for Me!

About My Friend's Little Sister Has It In for Me!

For high schooler Akiteru Oboshi, the whole youthful experience thing—like fun, friendships, and even having a girlfriend—is a complete waste of time. So when his best friend’s sister, Iroha Kohinata, keeps teasing him, Akiteru naturally finds it annoying.

HTB's My Friend's Little Sister Has It In for Me! is an animation and comedy series. Its one season of 12 episodes aired between October 2025 and December 2025.

The series is filed under romance, slice of life, school, and based on light novel. Haruki Ishiya appears as Akiteru Oboshi (voice), Sayumi Suzushiro as Iroha Kohinata (voice), Tomori Kusunoki as Mashiro Tsukinomori (voice), and Soma Saito as Ozuma Kohinata (voice).

It was produced by Asmik Ace, BLADE, and BS11. American members can watch it on Crunchyroll and Crunchyroll Amazon Channel.

Haganai: I Don't Have Many Friends, The Quintessential Quintuplets, and Toradora! make useful companions to My Friend's Little Sister Has It In for Me!, all filed under harem. It carries a TV-14 rating.